NT
Clinical Insight by NeuroThrottle
System Operational
Diagnostic Governance Platform · v1.0 Private Beta

AI in Pathology.
Governed. Auditable.
Institutionally Safe.

NT Clinical Insight does not compete with AI.
It makes AI usable within institutional boundaries — for the first time.

0 Cases Processed
Avg POSM Score
100% Audit Coverage
0 PHI Exposures
Live Simulation · Case #NT-2024-0847

Platform Architecture

Ten integrated layers process each case from raw image to validated signed report. All patient data remains within institutional boundaries at all times.

Core Engine
01 Input Layer LIVE
WSI: slide_247B.svs
Resolution: 40× · 2.1 GB
Metadata: 12 fields loaded
02 Privacy Layer SECURE
Pseudonymization: ✓ Applied
Data isolation: ✓ On-premise
PHI exported: None
03 Preprocessing RUNNING
Stain normalization: Macenko · H&E
Tissue mapping: 87% coverage
Quality score: 0.93
04 Signal Layer PENDING
Architecture
Atypia
Mitotic
Necrosis
POSM-PATH
SCS
MDC
MCA
CPI
RPI
Action Engine Awaiting analysis…
Orchestration · Copilot · Governance
07 API Orchestration STANDBY
GPT-4o
Claude
Gemini
Paige AI
Proscia
08 Diagnostic Copilot PENDING
Context-aware draft will appear here once POSM-PATH analysis is complete…
09 Professional Chat E2E ENCRYPTED
Dr. R. Morales Case shared for second opinion. IHC panel suggested.
You Reviewing. ER/PR borderline — escalating.
10 Human Oversight PATHOLOGIST
Authority: Final clinical sign-off
Audit: 0 entries logged
Status: Awaiting analysis

POSM-PATH Framework

A diagnostic stability scalar from 0.0 → 1.0. Unlike a raw classification score, POSM-PATH reflects whether a case is safe to finalize or requires intervention.

0.85 – 1.0 Stable routine_pass
0.65 – 0.84 Monitoring request_deeper_review
0.45 – 0.64 Alert suggest_IHC_panel + checklist
0.25 – 0.44 Critical flag_malignancy + senior_escalation
0.00 – 0.24 Collapse mandatory_audit + senior
posm/engine
def compute_posm(mdc, scs, mca):
    High = (
        0.8*rcs +
        0.5*mdc +
        0.9*xzd +
        0.1*cpi +
        0.1*rpi
    )

    # High confidence + contradictory signals
    if scs < 0.4 and mdc > 0:
        score *= 0

    # Hard cap: material adequacy override
    if mca < 0.3:
        score = min(score, 0.4)

    return round(score, 4)

Ungoverned AI vs. Governed

Informal AI Use Today
ChatGPT in a separate browser tab
No traceability or audit log
Patient data on external servers
No clinical context — starts from zero
Legally indefensible
WhatsApp for colleague consultation
Each hospital reinvents the workflow
NT Clinical Insight
Integrated within the diagnostic workflow
Full audit trail on every interaction
All data on-premise, PHI never leaves
POSM-PATH context always active
Auditable · traceable · GDPR · ENS · NIS2 · HIPAA · FISMA
Encrypted professional channel with traceability
Standardized governance layer

Request Access

Early access for pathology departments and digital health institutions. We review submissions selectively.